2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Cytochrome P450
  5. CYP1 Isoform
  6. CYP1 Inducer

CYP1 Inducer

CYP1 Inducers (2):

Cat. No. Product Name Effect Purity
  • HY-W762015
    1,2,3,6,7,8-Hexachlorodibenzofuran
    		Inducer
    1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 1.47 and 1.24 nM, respectively). 1,2,3,6,7,8-Hexachlorodibenzofuran reduces weight, induces thymic atrophy, and induces the expression of genes encoding the cytochrome P450 (CYP) isoform CYP1A1 and 4-chlorobiphenyl hydroxylase in rats (EC50s = 3.2, 0.9, 0.35, and 0.21 µmol/kg, respectively).
  • HY-103223
    Phortress
    		Inducer 99.25%
    Phortress is a high affinity AhR ligand that elicits antitumor activity by inducing transcription of CYP1A1.